Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 91252
Gene Symbol: SLC39A13
SLC39A13
CUI: C0235950
Disease: Zinc deficiency
Zinc deficiency 		0.210 Biomarker RGD Over-expression of Zip-13 mRNA in kidney and lung during dietary zinc deficiency in Wistar rats. 20859692

2011
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0235950
Disease: Zinc deficiency
Zinc deficiency 		0.200 Biomarker RGD The influence of gestational zinc deficiency on the fetal insulin-like growth factor axis in the rat. 20404036

2010
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0043325
Disease: Xanthomatosis
Xanthomatosis 		0.340 Biomarker RGD Hypercholesterolemia and atherosclerosis in low density lipoprotein receptor mutant rats. 22293196

2012
Entrez Id: 3897
Gene Symbol: L1CAM
L1CAM
CUI: C0265216
Disease: X-linked hydrocephalus syndrome
X-linked hydrocephalus syndrome 		1.000 Biomarker RGD The authors used this method to generate a transgenic rat L1cam knockout model of X-linked hydrocephalus (XLH) with human genetic etiology. 30738385

2019
Entrez Id: 18
Gene Symbol: ABAT
ABAT
CUI: C0037769
Disease: West Syndrome
West Syndrome 		0.210 Therapeutic RGD Infantile spasms (IS) have poor outcomes and limited treatment options, including vigabatrin, a γ-aminobutyric acid (GABA) aminotransferase inactivator. 24321005

2014
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0037769
Disease: West Syndrome
West Syndrome 		0.200 Biomarker RGD Proteomic analysis on infantile spasm and prenatal stress. 24994451

2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0043121
Disease: Wernicke Encephalopathy
Wernicke Encephalopathy 		0.200 Biomarker RGD Selective increase of neuronal cyclooxygenase-2 (COX-2) expression in vulnerable brain regions of rats with experimental Wernicke's encephalopathy: effect of nimesulide. 18481165

2008
Entrez Id: 590
Gene Symbol: BCHE
BCHE
CUI: C0043102
Disease: Weil Disease
Weil Disease 		0.200 Biomarker RGD Cholinesterases as markers of the inflammatory process in rats infected with Leptospira interrogans serovar Icterohaemorrhagiae. 21921108

2012
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0043102
Disease: Weil Disease
Weil Disease 		0.200 Biomarker RGD Cholinesterases as markers of the inflammatory process in rats infected with Leptospira interrogans serovar Icterohaemorrhagiae. 21921108

2012
Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C0043102
Disease: Weil Disease
Weil Disease 		0.200 Biomarker RGD Adenosine deaminase activity in serum, erythrocytes and lymphocytes of rats infected with Leptospira icterohaemorrhagiae. 21320715

2012
Entrez Id: 5121
Gene Symbol: PCP4
PCP4
CUI: C0043065
Disease: Water-Electrolyte Imbalance
Water-Electrolyte Imbalance 		0.200 Biomarker RGD Gene expression in the rat supraoptic nucleus induced by chronic hyperosmolality versus hyposmolality. 11003989

2000
Entrez Id: 79001
Gene Symbol: VKORC1
VKORC1
CUI: C2608079
Disease: WARFARIN SENSITIVITY (disorder)
WARFARIN SENSITIVITY (disorder) 		0.300 Biomarker RGD Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. 14765194

2004
Entrez Id: 6256
Gene Symbol: RXRA
RXRA
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Regulation of retinoic acid receptors alpha, beta and retinoid X receptor alpha after sciatic nerve injury. 16782282

2006
Entrez Id: 4763
Gene Symbol: NF1
NF1
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD After nerve transection, no alteration in NF1 message level was detected, but neurofibromin levels increased, as assessed by immunohistochemistry and Western blotting, suggesting that, in vivo, neurofibromin expression in Schwann cells is post-transcriptionally induced during Wallerian degeneration. 8847098

1995
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration. 9030624

1997
Entrez Id: 5321
Gene Symbol: PLA2G4A
PLA2G4A
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD These results provide direct evidence of an important role for cPLA(2) in Wallerian degeneration. 14664823

2003
Entrez Id: 4744
Gene Symbol: NEFH
NEFH
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Selective solubilization of high-molecular-mass neurofilament subunit during nerve regeneration. 10646539

2000
Entrez Id: 4741
Gene Symbol: NEFM
NEFM
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Selective solubilization of high-molecular-mass neurofilament subunit during nerve regeneration. 10646539

2000
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Expression of genes encoding receptors for IgG (FcRIII) and for C3b/C4b (Crry) in rat sciatic nerve during development and Wallerian degeneration. 1533683

1992
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Selective solubilization of high-molecular-mass neurofilament subunit during nerve regeneration. 10646539

2000
Entrez Id: 4099
Gene Symbol: MAG
MAG
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Sequential loss of myelin proteins during Wallerian degeneration in the rat spinal cord. 12730963

2003
Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Distribution and expression of tissue inhibitors of metalloproteinase in dorsal root entry zone and dorsal column after dorsal root injury. 16683235

2006
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Distribution and expression of tissue inhibitors of metalloproteinase in dorsal root entry zone and dorsal column after dorsal root injury. 16683235

2006
Entrez Id: 6428
Gene Symbol: SRSF3
SRSF3
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Differentially expressed genes after peripheral nerve injury. 8568916

1995
Entrez Id: 3606
Gene Symbol: IL18
IL18
CUI: C0043020
Disease: Wallerian Degeneration
Wallerian Degeneration 		0.200 Biomarker RGD Induction of the proinflammatory cytokine interleukin-18 by axonal injury. 11494369

2001